Glaucoma: Collaborative Normal Tension Glaucoma Study: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: Collaborative Normal Tension Glaucoma Study

Sample item

In the Collaborative Normal-Tension Glaucoma Study, lowering intraocular pressure by roughly what proportion from baseline slowed progression of field loss?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. About 30 percent

That trial randomised eyes with normal-tension glaucoma to treatment or observation and showed benefit when pressure was reduced by about 30 percent. This is why a percentage reduction from baseline, and not a fixed target below 21 mmHg, guides treatment in normal-tension glaucoma.

Option by option

  • A. About 10 percent

    A reduction of 10 percent was not the trial target and is smaller than the effective reduction.

  • B. About 30 percent (correct)

    Correct. A reduction of about 30 percent was the treatment goal that slowed progression.

  • C. About 50 percent

    A reduction of 50 percent is more than was targeted and is rarely achievable with medication alone.

  • D. About 70 percent

    A reduction of 70 percent is not achievable in eyes whose baseline pressure is already within the normal range.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, About 30 percent. That trial randomised eyes with normal-tension glaucoma to treatment or observation and showed benefit when pressure was reduced by about 30 percent.

Why is "About 10 percent" not the answer?

A reduction of 10 percent was not the trial target and is smaller than the effective reduction.

Why is "About 50 percent" not the answer?

A reduction of 50 percent is more than was targeted and is rarely achievable with medication alone.

Why is "About 70 percent" not the answer?

A reduction of 70 percent is not achievable in eyes whose baseline pressure is already within the normal range.

What concept does this question test?

It tests Glaucoma: Collaborative Normal Tension Glaucoma Study in Ophthalmology. This is why a percentage reduction from baseline, and not a fixed target below 21 mmHg, guides treatment in normal-tension glaucoma.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: Collaborative Normal Tension Glaucoma Study?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.