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Ophthalmology · Community ophthalmology: chlamydial ophthalmia neonatorum
Sample itemA neonate born at home to a mother with untreated genital infection develops mucopurulent discharge and lid swelling on day 9. Cultures for gonococcus are negative. What is the appropriate treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Oral erythromycin for the baby, with treatment of the parents
Chlamydial conjunctivitis appears 5 to 14 days after birth, later than chemical or gonococcal disease, and can be associated with pneumonitis. Systemic macrolide treatment is needed, because topical treatment does not clear the nasopharyngeal infection. Both parents need treatment to prevent reinfection.
Option by option
A. Intravenous ceftriaxone only
Ceftriaxone is aimed at gonococcal infection, which cultures excluded.
B. Oral erythromycin for the baby, with treatment of the parents (correct)
Correct. Oral erythromycin treats chlamydial ophthalmia and its systemic reservoir.
C. Silver nitrate drops
Silver nitrate causes chemical conjunctivitis and is not a treatment.
D. Topical antibiotic drops alone
Topical drops alone do not clear nasopharyngeal carriage and risk pneumonitis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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