Try it
Pediatrics · Paediatric infections: hookworm anaemia
Sample itemA barefoot 7-year-old from a rural area has marked pallor, pedal oedema, a microcytic hypochromic smear and eosinophilia. Stool contains ova with a thin shell and a segmented embryo. How does this infection cause anaemia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Chronic intestinal blood loss from worm attachment
Hookworms (Ancylostoma duodenale and Necator americanus) attach to the small-bowel mucosa and feed on blood, causing chronic iron-deficiency anaemia and protein loss with oedema. Infection occurs through skin penetration by larvae. Treatment is albendazole with iron supplementation.
Option by option
A. Chronic intestinal blood loss from worm attachment (correct)
Correct. Chronic blood loss from attached worms causes iron deficiency.
B. Marrow suppression by larval toxins
Marrow suppression is not a feature of hookworm disease.
C. Intravascular haemolysis
Haemolysis is not the mechanism; the smear shows iron deficiency.
D. Vitamin B12 malabsorption
B12 deficiency is linked to fish tapeworm and not to hookworm.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Pediatrics questions
- Congenital heart diseaseWhich is the most common cyanotic congenital heart disease presenting beyond the neonata…
- NutritionWhich feature most clearly distinguishes kwashiorkor from marasmus?
- NeonatologyA newborn becomes visibly jaundiced in the first 24 hours of life. What is the most like…
- Diarrhoeal diseasesA child with diarrhoea has 'some dehydration'. What is the recommended initial management?