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Pediatrics · Paediatric emergencies: acute severe asthma add-on therapy
Sample itemA 7-year-old with acute severe asthma has received three doses of nebulised salbutamol with ipratropium and oral prednisolone. He remains breathless with SpO2 91 percent and poor air entry. Which add-on is recommended?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous magnesium sulphate
In acute severe asthma that fails to respond to repeated bronchodilators and steroids, intravenous magnesium sulphate is the recommended next step. It relaxes bronchial smooth muscle, and the child needs monitoring for hypotension.
Option by option
A. Intravenous antibiotics
Antibiotics are not indicated unless there is evidence of bacterial infection.
B. Intravenous magnesium sulphate (correct)
Correct. Magnesium sulphate is the recommended add-on for severe asthma not responding to initial treatment.
C. Nebulised sodium cromoglycate
Cromoglycate is a preventive agent and has no role in an acute attack.
D. Oral montelukast
Montelukast has no established role in an acute severe attack.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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