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Psychiatry · Mood disorders: ECT in pregnancy
Sample itemA woman in the second trimester of pregnancy has severe psychotic depression with refusal of food and fluids and active suicidal intent. Medicines carry concerns and she is losing weight rapidly. What is the most appropriate treatment?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. ECT with obstetric monitoring and anaesthetic precautions
ECT is an effective and relatively safe treatment for severe depression in pregnancy, especially when there is psychosis, suicidality or refusal of food. It is given with precautions such as fetal monitoring, aspiration prevention and avoidance of aortocaval compression.
Option by option
A. Lithium and valproate together
Both lithium and valproate carry teratogenic risk and are not first choices here.
B. ECT with obstetric monitoring and anaesthetic precautions (correct)
Correct. ECT is the rapid and relatively safe option in life-threatening depression in pregnancy.
C. Withholding all treatment until delivery
Delay is dangerous because of the risk of suicide and starvation.
D. Long-term benzodiazepines alone
Benzodiazepines do not treat psychotic depression and are not appropriate as sole treatment.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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