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Psychiatry · Anxiety and related disorders: organic cause of anxiety
Sample itemA 32-year-old woman has anxiety, palpitations, heat intolerance, weight loss despite good appetite and a fine tremor. Which first investigation is most useful before labelling her as having generalised anxiety disorder?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Serum TSH
Hyperthyroidism commonly mimics anxiety, with tremor, heat intolerance and weight loss pointing to it. A suppressed TSH with raised thyroid hormones would confirm it, and anxiety should be diagnosed only after medical causes are excluded.
Option by option
A. Fasting lipid profile
A lipid profile does not explain these symptoms.
B. Serum TSH (correct)
Correct. TSH screens for hyperthyroidism, the most likely medical mimic here.
C. Chest radiograph
A chest radiograph is not a first investigation for these symptoms.
D. Serum vitamin B12
Low B12 causes neuropsychiatric and haematological problems, not this hypermetabolic picture.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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