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Psychiatry · Organic mental disorders: Parkinson disease dementia treatment
Sample itemA 74-year-old man with Parkinson disease for eight years develops progressive cognitive decline, fluctuating attention and visual hallucinations. Which drug is licensed to treat the dementia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Rivastigmine
Parkinson disease dementia involves a marked cholinergic deficit, and rivastigmine, a cholinesterase inhibitor, is the licensed treatment. Anticholinergic antiparkinsonian drugs worsen cognition, and conventional antipsychotics such as haloperidol worsen motor features.
Option by option
A. Rivastigmine (correct)
Correct. A cholinesterase inhibitor improves cognition and hallucinations in this dementia.
B. Haloperidol
Haloperidol blocks D2 receptors and can severely worsen parkinsonism.
C. Trihexyphenidyl
Trihexyphenidyl is an anticholinergic and worsens confusion and cognition.
D. Memantine
Memantine has weaker evidence and is not the licensed treatment for this condition.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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