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Psychiatry · Eating and sleep disorders: multiple sleep latency test in narcolepsy
Sample itemA 22-year-old with excessive daytime sleepiness undergoes overnight polysomnography followed by a daytime nap study with five nap opportunities. Which result supports narcolepsy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Mean sleep latency of 8 minutes or less with two or more sleep-onset REM periods
The Multiple Sleep Latency Test measures how quickly a person falls asleep across several naps. In narcolepsy the mean latency is short (8 minutes or less) and REM sleep appears within 15 minutes of sleep onset in at least two naps. A latency near 20 minutes is normal.
Option by option
A. Mean sleep latency of 8 minutes or less with two or more sleep-onset REM periods (correct)
Correct. Short latency with repeated sleep-onset REM is the characteristic result.
B. Mean sleep latency of 20 minutes with no REM during naps
A mean latency of 20 minutes without REM is a normal result.
C. Reduced sleep latency with only N3 sleep in naps
N3-only naps do not represent the REM intrusion typical of narcolepsy.
D. Normal REM latency at night and normal nap latency
Normal latencies argue against pathological sleepiness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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