Inhalational agents: enflurane: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Inhalational agents: enflurane

Sample item

Which volatile agent can produce epileptiform EEG activity, especially with hyperventilation?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Enflurane

Enflurane at high concentration and low PaCO2 produces spike and wave activity and sometimes seizure-like movements. It is therefore avoided in epilepsy.

Option by option

  • A. Halothane

    Halothane is not epileptogenic.

  • B. Isoflurane

    Isoflurane suppresses EEG activity.

  • C. Sevoflurane at 1 MAC

    Sevoflurane can cause some spikes at high dose but is not classically linked.

  • D. Enflurane (correct)

    Correct. Enflurane is epileptogenic.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is D, Enflurane. Enflurane at high concentration and low PaCO2 produces spike and wave activity and sometimes seizure-like movements.

Why is "Halothane" not the answer?

Halothane is not epileptogenic.

Why is "Isoflurane" not the answer?

Isoflurane suppresses EEG activity.

Why is "Sevoflurane at 1 MAC" not the answer?

Sevoflurane can cause some spikes at high dose but is not classically linked.

What concept does this question test?

It tests Inhalational agents: enflurane in Anaesthesia. It is therefore avoided in epilepsy.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Inhalational agents: enflurane?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.