Muscle relaxants: myasthenia gravis: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Anaesthesia · Muscle relaxants: myasthenia gravis

Sample item

How does a patient with myasthenia gravis respond to neuromuscular blockers?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Sensitive to non-depolarisers and relatively resistant to suxamethonium

Reduced numbers of functional acetylcholine receptors mean a small dose of non-depolariser causes a profound block, whereas a larger dose of suxamethonium is required for effect. Doses of non-depolarisers are reduced to 10 to 20% and monitoring is essential.

Option by option

  • A. No change to either

    There is a clear change.

  • B. Sensitive to non-depolarisers and relatively resistant to suxamethonium (correct)

    Correct. Sensitive to non-depolarisers and resistant to suxamethonium.

  • C. Sensitive to both equally

    The sensitivity is not equal.

  • D. Resistant to non-depolarisers and sensitive to suxamethonium

    The reverse pattern describes no common condition.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Anaesthesia questions

Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is B, Sensitive to non-depolarisers and relatively resistant to suxamethonium. Reduced numbers of functional acetylcholine receptors mean a small dose of non-depolariser causes a profound block, whereas a larger dose of suxamethonium is required for effect.

Why is "No change to either" not the answer?

There is a clear change.

Why is "Sensitive to both equally" not the answer?

The sensitivity is not equal.

Why is "Resistant to non-depolarisers and sensitive to suxamethonium" not the answer?

The reverse pattern describes no common condition.

What concept does this question test?

It tests Muscle relaxants: myasthenia gravis in Anaesthesia. Doses of non-depolarisers are reduced to 10 to 20% and monitoring is essential.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Muscle relaxants: myasthenia gravis?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.