Ototoxicity: loop diuretics: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Ototoxicity: loop diuretics

Sample item

Which ototoxic drug typically produces hearing loss that is often reversible after stopping the drug?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Furosemide

Loop diuretics affect the stria vascularis and the loss is usually temporary, but it can be permanent with high doses or with aminoglycosides. Aminoglycosides and cisplatin destroy hair cells and cause permanent loss.

Option by option

  • A. Neomycin

    Neomycin is strongly cochleotoxic and the damage is permanent.

  • B. Furosemide (correct)

    Correct. Loop diuretic ototoxicity is usually reversible.

  • C. Gentamicin

    Gentamicin is mainly vestibulotoxic and causes permanent damage.

  • D. Cisplatin

    Cisplatin causes permanent high-frequency hair cell loss.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this ENT question

What is the answer to this ENT question?

The best answer is B, Furosemide. Loop diuretics affect the stria vascularis and the loss is usually temporary, but it can be permanent with high doses or with aminoglycosides.

Why is "Neomycin" not the answer?

Neomycin is strongly cochleotoxic and the damage is permanent.

Why is "Gentamicin" not the answer?

Gentamicin is mainly vestibulotoxic and causes permanent damage.

Why is "Cisplatin" not the answer?

Cisplatin causes permanent high-frequency hair cell loss.

What concept does this question test?

It tests Ototoxicity: loop diuretics in ENT. Aminoglycosides and cisplatin destroy hair cells and cause permanent loss.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Ototoxicity: loop diuretics?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.