Salivary glands: Sjogren syndrome: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

ENT · Salivary glands: Sjogren syndrome

Sample item

A middle-aged woman has dry eyes, dry mouth and bilateral parotid enlargement. Which autoantibodies are characteristic?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Anti-Ro (SSA) and anti-La (SSB)

Sjogren syndrome features lymphocytic infiltration of lacrimal and salivary glands with anti-Ro and anti-La antibodies. There is an increased risk of MALT lymphoma, and the Schirmer test is abnormal.

Option by option

  • A. Anti-centromere only

    Anti-centromere relates to limited scleroderma.

  • B. Anti-Scl-70

    Anti-Scl-70 relates to diffuse scleroderma.

  • C. Anti-Jo-1

    Anti-Jo-1 relates to polymyositis.

  • D. Anti-Ro (SSA) and anti-La (SSB) (correct)

    Correct. Anti-Ro and anti-La are typical.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More ENT questions

Questions about this ENT question

What is the answer to this ENT question?

The best answer is D, Anti-Ro (SSA) and anti-La (SSB). Sjogren syndrome features lymphocytic infiltration of lacrimal and salivary glands with anti-Ro and anti-La antibodies.

Why is "Anti-centromere only" not the answer?

Anti-centromere relates to limited scleroderma.

Why is "Anti-Scl-70" not the answer?

Anti-Scl-70 relates to diffuse scleroderma.

Why is "Anti-Jo-1" not the answer?

Anti-Jo-1 relates to polymyositis.

What concept does this question test?

It tests Salivary glands: Sjogren syndrome in ENT. There is an increased risk of MALT lymphoma, and the Schirmer test is abnormal.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Salivary glands: Sjogren syndrome?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.