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ENT · Paediatric ENT: congenital CMV
Sample itemWhat is the commonest non-genetic cause of congenital sensorineural hearing loss?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Congenital cytomegalovirus infection
Congenital CMV is the commonest acquired cause, and the loss can be late-onset or progressive, so follow-up audiometry is needed. Diagnosis is by PCR on urine, saliva or dried blood spot in the first three weeks, and valganciclovir may be given in symptomatic infants.
Option by option
A. Congenital cytomegalovirus infection (correct)
Correct. CMV is the commonest non-genetic cause.
B. Rubella
Rubella is now uncommon where vaccination is available.
C. Syphilis
Syphilis is a rarer cause.
D. Toxoplasmosis
Toxoplasmosis is a less common cause.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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