Emergency: hereditary angioedema: practice question

A ENT question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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ENT · Emergency: hereditary angioedema

Sample item

A man has recurrent episodes of non-itchy facial and laryngeal swelling without urticaria, with a family history. Which therapy is appropriate for an acute laryngeal attack?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. C1 esterase inhibitor concentrate

Hereditary angioedema results from C1 inhibitor deficiency, with bradykinin-mediated swelling that does not respond well to adrenaline, antihistamines or steroids. Acute attacks are treated with C1 inhibitor concentrate or icatibant, and the airway is secured if needed.

Option by option

  • A. Antibiotics

    Antibiotics do not apply.

  • B. C1 esterase inhibitor concentrate (correct)

    Correct. C1 inhibitor replacement treats an acute attack.

  • C. Oral steroids only

    Oral steroids are ineffective.

  • D. Subcutaneous antihistamine only

    Antihistamines are ineffective in bradykinin-mediated swelling.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More ENT questions

Questions about this ENT question

What is the answer to this ENT question?

The best answer is B, C1 esterase inhibitor concentrate. Hereditary angioedema results from C1 inhibitor deficiency, with bradykinin-mediated swelling that does not respond well to adrenaline, antihistamines or steroids.

Why is "Antibiotics" not the answer?

Antibiotics do not apply.

Why is "Oral steroids only" not the answer?

Oral steroids are ineffective.

Why is "Subcutaneous antihistamine only" not the answer?

Antihistamines are ineffective in bradykinin-mediated swelling.

What concept does this question test?

It tests Emergency: hereditary angioedema in ENT. Acute attacks are treated with C1 inhibitor concentrate or icatibant, and the airway is secured if needed.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Emergency: hereditary angioedema?

Learn tuning fork results and audiogram patterns by sketching them. Then use the flashcards and the other ENT questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.