Antenatal care: pre-gestational diabetes: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Antenatal care: pre-gestational diabetes

Sample item

Which congenital anomaly is most specific for maternal pre-gestational diabetes?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Caudal regression syndrome

Caudal regression (sacral agenesis) is the most characteristic anomaly in diabetic embryopathy, though cardiac defects are the commonest overall. The risk relates to periconceptional glycaemic control, so HbA1c should ideally be below 6.5 per cent before conception.

Option by option

  • A. Gastroschisis

    Gastroschisis is linked to young maternal age and is sporadic.

  • B. Duodenal atresia

    Duodenal atresia is linked to Down syndrome.

  • C. Caudal regression syndrome (correct)

    Correct. Sacral agenesis is highly specific for poorly controlled maternal diabetes.

  • D. Cleft palate

    Cleft palate is not specific to diabetes.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is C, Caudal regression syndrome. Caudal regression (sacral agenesis) is the most characteristic anomaly in diabetic embryopathy, though cardiac defects are the commonest overall.

Why is "Gastroschisis" not the answer?

Gastroschisis is linked to young maternal age and is sporadic.

Why is "Duodenal atresia" not the answer?

Duodenal atresia is linked to Down syndrome.

Why is "Cleft palate" not the answer?

Cleft palate is not specific to diabetes.

What concept does this question test?

It tests Antenatal care: pre-gestational diabetes in OBG. The risk relates to periconceptional glycaemic control, so HbA1c should ideally be below 6.5 per cent before conception.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antenatal care: pre-gestational diabetes?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.