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OBG · Medical disorders in pregnancy: hepatitis B
Sample itemA newborn is born to a HBsAg and HBeAg positive mother. What is the recommended management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Hepatitis B immunoglobulin and hepatitis B vaccine within 12 hours of birth
Neonatal passive-active immunoprophylaxis (HBIG plus vaccine within 12 hours, followed by the vaccine schedule) prevents over 90 per cent of perinatal transmission. Mothers with a high viral load may receive tenofovir in the third trimester. Breastfeeding is safe after immunoprophylaxis.
Option by option
A. Immediate caesarean for all
Caesarean section does not reliably prevent transmission.
B. Hepatitis B immunoglobulin and hepatitis B vaccine within 12 hours of birth (correct)
Correct. Early HBIG and vaccine prevent vertical transmission.
C. Stop breastfeeding permanently
Breastfeeding is not contraindicated after prophylaxis.
D. Vaccine at 6 weeks only
Delaying the vaccine to 6 weeks misses the window.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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