Hypertensive disorders: biomarkers: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Hypertensive disorders: biomarkers

Sample item

A sFlt-1 to PlGF ratio below 38 in a woman with suspected pre-eclampsia is used to:

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Rule out pre-eclampsia in the next week

A low sFlt-1/PlGF ratio (below 38) has a high negative predictive value for excluding pre-eclampsia in the following week in women with suspected disease. High ratios predict need for delivery within weeks. It is an adjunct and not part of standard Indian practice.

Option by option

  • A. Diagnose gestational diabetes

    It is not used for diabetes.

  • B. Confirm eclampsia

    It does not confirm eclampsia.

  • C. Rule out pre-eclampsia in the next week (correct)

    Correct. A low ratio has a high negative predictive value.

  • D. Predict neural tube defect

    It is not related to neural tube defects.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this OBG question

What is the answer to this OBG question?

The best answer is C, Rule out pre-eclampsia in the next week. A low sFlt-1/PlGF ratio (below 38) has a high negative predictive value for excluding pre-eclampsia in the following week in women with suspected disease.

Why is "Diagnose gestational diabetes" not the answer?

It is not used for diabetes.

Why is "Confirm eclampsia" not the answer?

It does not confirm eclampsia.

Why is "Predict neural tube defect" not the answer?

It is not related to neural tube defects.

What concept does this question test?

It tests Hypertensive disorders: biomarkers in OBG. High ratios predict need for delivery within weeks. It is an adjunct and not part of standard Indian practice.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hypertensive disorders: biomarkers?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.