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OBG · Antepartum haemorrhage: abruption and DIC
Sample itemIn concealed placental abruption, which laboratory finding best predicts severe PPH and coagulopathy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Low plasma fibrinogen (below 200 mg/dL)
Retroplacental clot consumes fibrinogen, and a level below 200 mg/dL is a strong predictor of severe haemorrhage. A bedside clot observation test (failure to clot in 7 to 10 minutes) is a simple indicator. Treatment is delivery with blood products including cryoprecipitate.
Option by option
A. Low blood urea
Urea is not predictive.
B. High haemoglobin
Haemoglobin may be normal early.
C. Low plasma fibrinogen (below 200 mg/dL) (correct)
Correct. Hypofibrinogenaemia predicts severe bleeding.
D. High platelet count
Platelets fall, not rise, in DIC.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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