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OBG · Gynaecological oncology: ovarian cancer treatment
Sample itemThe standard adjuvant chemotherapy for epithelial ovarian cancer after debulking surgery is:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Carboplatin and paclitaxel
Cytoreductive surgery (staging, hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and removal of visible disease) is followed by platinum-taxane chemotherapy. BRCA-mutated disease benefits from PARP inhibitor maintenance. BEP is for germ cell tumours.
Option by option
A. BEP regimen
BEP is for germ cell tumours.
B. Carboplatin and paclitaxel (correct)
Correct. Carboplatin plus paclitaxel is standard.
C. Tamoxifen
Tamoxifen is not standard first-line.
D. Methotrexate alone
Methotrexate is for GTN.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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