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Ophthalmology · Conjunctiva: phlyctenular
Sample itemA child with a tuberculous contact has a small nodule at the limbus with surrounding hyperaemia. What is the mechanism of phlyctenular conjunctivitis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Delayed hypersensitivity to microbial antigens
Phlyctenules are type IV delayed hypersensitivity reactions to antigens of tubercle bacilli or staphylococci. Treatment is topical steroids and treating the underlying cause.
Option by option
A. Viral replication in epithelium
It is not a viral epithelial infection.
B. Direct bacterial invasion
The organism is not actively invading the tissue.
C. Immediate hypersensitivity to pollen
Immediate hypersensitivity causes vernal and hay fever types.
D. Delayed hypersensitivity to microbial antigens (correct)
Correct. This is a delayed hypersensitivity response.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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