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Ophthalmology · Corneal ulcer: fungal
Sample itemA farmer with a vegetable matter injury develops a corneal ulcer with feathery margins and satellite lesions. Which drug is the first-line topical treatment for filamentous fungus?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Natamycin 5 percent
Filamentous fungi such as Aspergillus and Fusarium cause these ulcers, and natamycin is the standard topical agent. Steroids worsen fungal ulcers and must be avoided.
Option by option
A. Acyclovir ointment
Acyclovir is an antiviral.
B. Natamycin 5 percent (correct)
Correct. Natamycin is the drug of choice for filamentous fungal keratitis.
C. Chlorhexidine alone
Chlorhexidine is used for Acanthamoeba.
D. Moxifloxacin
Fluoroquinolones have no antifungal action.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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