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Ophthalmology · Cornea: Kayser-Fleischer ring
Sample itemA 17-year-old with tremor and hepatic dysfunction shows a golden brown ring at the corneal periphery. At which layer is the copper deposited?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Descemet's membrane
Copper deposits in the peripheral Descemet's membrane in Wilson disease. Slit-lamp examination is needed, and the ring may be absent in hepatic presentations without neurological disease.
Option by option
A. Anterior stroma
The stroma is not the site of copper deposition.
B. Descemet's membrane (correct)
Correct. The ring lies in Descemet's membrane.
C. Bowman's layer
Bowman's layer is the site of calcium in band keratopathy.
D. Epithelium
The epithelium is not the site.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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