Glaucoma: carbonic anhydrase inhibitors: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: carbonic anhydrase inhibitors

Sample item

Which adverse effect is associated with oral acetazolamide?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Hypokalaemic metabolic acidosis with paraesthesia

Acetazolamide causes bicarbonate loss, hypokalaemia, acidosis, paraesthesia, renal stones and sulfonamide-type reactions. Bronchospasm is a beta-blocker effect.

Option by option

  • A. Hyperkalaemia and alkalosis

    The electrolyte and acid-base changes are the reverse.

  • B. Hypokalaemic metabolic acidosis with paraesthesia (correct)

    Correct. Acidosis, hypokalaemia and tingling are typical.

  • C. Bradycardia and bronchospasm

    Bradycardia and bronchospasm occur with timolol.

  • D. Hypernatraemia

    Hypernatraemia is not characteristic.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, Hypokalaemic metabolic acidosis with paraesthesia. Acetazolamide causes bicarbonate loss, hypokalaemia, acidosis, paraesthesia, renal stones and sulfonamide-type reactions.

Why is "Hyperkalaemia and alkalosis" not the answer?

The electrolyte and acid-base changes are the reverse.

Why is "Bradycardia and bronchospasm" not the answer?

Bradycardia and bronchospasm occur with timolol.

Why is "Hypernatraemia" not the answer?

Hypernatraemia is not characteristic.

What concept does this question test?

It tests Glaucoma: carbonic anhydrase inhibitors in Ophthalmology. Bronchospasm is a beta-blocker effect.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: carbonic anhydrase inhibitors?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.