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Ophthalmology · Glaucoma: trabeculectomy
Sample itemWhich adjunct is commonly applied during trabeculectomy to reduce scarring of the filtering bleb?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Mitomycin C
Mitomycin C or 5-fluorouracil inhibits fibroblast proliferation and so lowers the rate of bleb failure. A risk of antimetabolite use is thin avascular blebs and late bleb leaks or infection.
Option by option
A. Mitomycin C (correct)
Correct. Antimetabolite use improves bleb survival.
B. Atropine
Atropine is a cycloplegic used in malignant glaucoma.
C. Timolol
Timolol is a beta-blocker.
D. Pilocarpine
Pilocarpine is a miotic antiglaucoma drug.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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