Glaucoma: low-tension drug effect: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Glaucoma: low-tension drug effect

Sample item

Which topical antiglaucoma drug lowers IOP by inhibiting carbonic anhydrase in the ciliary body?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Dorzolamide

Topical dorzolamide and brinzolamide inhibit carbonic anhydrase in the ciliary body and lower aqueous production. They may cause stinging, bitter taste and rarely sulfonamide-like allergy.

Option by option

  • A. Brimonidine

    Brimonidine is an alpha-2 agonist.

  • B. Pilocarpine

    Pilocarpine acts on trabecular outflow.

  • C. Dorzolamide (correct)

    Correct. Dorzolamide is a topical carbonic anhydrase inhibitor.

  • D. Latanoprost

    Latanoprost acts through uveoscleral outflow.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is C, Dorzolamide. Topical dorzolamide and brinzolamide inhibit carbonic anhydrase in the ciliary body and lower aqueous production.

Why is "Brimonidine" not the answer?

Brimonidine is an alpha-2 agonist.

Why is "Pilocarpine" not the answer?

Pilocarpine acts on trabecular outflow.

Why is "Latanoprost" not the answer?

Latanoprost acts through uveoscleral outflow.

What concept does this question test?

It tests Glaucoma: low-tension drug effect in Ophthalmology. They may cause stinging, bitter taste and rarely sulfonamide-like allergy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glaucoma: low-tension drug effect?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.