Uveitis: birdshot: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Uveitis: birdshot

Sample item

A middle-aged woman has floaters, night vision problems and multiple cream-coloured oval choroidal lesions radiating from the disc. Which HLA type is strongly associated?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. HLA-A29

Birdshot chorioretinopathy is a posterior uveitis with a very strong association with HLA-A29. It requires immunosuppression because of chronic progressive damage.

Option by option

  • A. HLA-A29 (correct)

    Correct. HLA-A29 is nearly universal in birdshot.

  • B. HLA-B51

    HLA-B51 is for Behcet disease.

  • C. HLA-DR2

    HLA-DR2 is not the key association.

  • D. HLA-B27

    HLA-B27 is for acute anterior uveitis.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is A, HLA-A29. Birdshot chorioretinopathy is a posterior uveitis with a very strong association with HLA-A29.

Why is "HLA-B51" not the answer?

HLA-B51 is for Behcet disease.

Why is "HLA-DR2" not the answer?

HLA-DR2 is not the key association.

Why is "HLA-B27" not the answer?

HLA-B27 is for acute anterior uveitis.

What concept does this question test?

It tests Uveitis: birdshot in Ophthalmology. It requires immunosuppression because of chronic progressive damage.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Uveitis: birdshot?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.