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Ophthalmology · Pupil: third nerve palsy
Sample itemA patient has sudden headache, ptosis, a dilated fixed pupil and a down-and-out eye. What is the most important cause to exclude?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Posterior communicating artery aneurysm
Pupil involvement indicates compression of the superficial parasympathetic fibres, and a PCom aneurysm is the emergency. Diabetic third nerve palsy typically spares the pupil.
Option by option
A. Myasthenia gravis
Myasthenia does not cause pupillary changes.
B. Horner syndrome
Horner has miosis.
C. Diabetic microvascular neuropathy
Diabetic palsy usually spares the pupil.
D. Posterior communicating artery aneurysm (correct)
Correct. A pupil-involving palsy needs urgent vascular imaging.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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