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Ophthalmology · Motility: internuclear ophthalmoplegia
Sample itemA young woman with multiple sclerosis cannot adduct her right eye on left gaze, while the left eye abducts with nystagmus. Where is the lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Right medial longitudinal fasciculus
Internuclear ophthalmoplegia is named for the side of the lesion in the MLF, which fails to carry signals from the contralateral abducens nucleus to the ipsilateral medial rectus subnucleus. Convergence is typically preserved.
Option by option
A. Right abducens nucleus
An abducens nucleus lesion causes a conjugate gaze palsy.
B. Left medial longitudinal fasciculus
A left MLF lesion impairs left adduction.
C. Right medial longitudinal fasciculus (correct)
Correct. Failure to adduct on the right indicates a right MLF lesion.
D. Right oculomotor nerve
An oculomotor nerve lesion would impair convergence as well.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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