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Ophthalmology · Orbit: thyroid eye disease
Sample itemA woman with Graves disease has lid retraction, proptosis and lid lag on downgaze. What is the commonest cause of unilateral or bilateral proptosis in adults?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Thyroid eye disease
Thyroid eye disease is the commonest cause of proptosis in adults and is due to autoimmune inflammation of orbital fat and muscles. Lid lag is von Graefe sign and lid retraction is Dalrymple sign.
Option by option
A. Thyroid eye disease (correct)
Correct. It is the leading cause in adults.
B. Orbital cellulitis
Orbital cellulitis presents acutely with fever.
C. Dermoid cyst
Dermoid cysts are congenital and usually small.
D. Rhabdomyosarcoma
Rhabdomyosarcoma is a childhood tumour.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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