Pharmacology: anti-VEGF: practice question

A Ophthalmology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Ophthalmology · Pharmacology: anti-VEGF

Sample item

Which agent is an intravitreal anti-VEGF drug commonly used off label for retinal disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Bevacizumab

Bevacizumab is a full-length antibody to VEGF-A that is widely used off label. Ranibizumab and aflibercept are approved agents, and endophthalmitis is a rare procedural risk.

Option by option

  • A. Timolol

    Timolol is a beta-blocker.

  • B. Bevacizumab (correct)

    Correct. Bevacizumab blocks VEGF-A.

  • C. Natamycin

    Natamycin is an antifungal.

  • D. Atropine

    Atropine is a cycloplegic.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Ophthalmology questions

Questions about this Ophthalmology question

What is the answer to this Ophthalmology question?

The best answer is B, Bevacizumab. Bevacizumab is a full-length antibody to VEGF-A that is widely used off label.

Why is "Timolol" not the answer?

Timolol is a beta-blocker.

Why is "Natamycin" not the answer?

Natamycin is an antifungal.

Why is "Atropine" not the answer?

Atropine is a cycloplegic.

What concept does this question test?

It tests Pharmacology: anti-VEGF in Ophthalmology. Ranibizumab and aflibercept are approved agents, and endophthalmitis is a rare procedural risk.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Pharmacology: anti-VEGF?

Group the red eye by what to examine and what the pupil does. Then use the flashcards and the other Ophthalmology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.