Fractures: bone grafting: practice question

A Orthopaedics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Orthopaedics · Fractures: bone grafting

Sample item

Which property of cancellous autograft makes it the gold standard for bone grafting?

AIt provides only a scaffoldBIt provides osteogenic cells, osteoinductive factors and an osteoconductive scaffoldCIt is acellular and immune-privilegedDIt provides structural strength only

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. It provides osteogenic cells, osteoinductive factors and an osteoconductive scaffold

Autograft, commonly harvested from the iliac crest, is the only graft that provides all three properties: osteogenesis by living cells, osteoinduction by growth factors, and osteoconduction by a scaffold. Its drawbacks are limited supply and donor site morbidity.

Option by option

A. It provides only a scaffold
A scaffold alone describes osteoconductive material such as hydroxyapatite.
B. It provides osteogenic cells, osteoinductive factors and an osteoconductive scaffold (correct)
Correct. Autograft supplies all three properties.
C. It is acellular and immune-privileged
Autograft contains living cells, so it is not acellular.
D. It provides structural strength only
Cortical grafts provide strength, whereas cancellous graft is for biology.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Orthopaedics question

What is the answer to this Orthopaedics question?

The best answer is B, It provides osteogenic cells, osteoinductive factors and an osteoconductive scaffold. Autograft, commonly harvested from the iliac crest, is the only graft that provides all three properties: osteogenesis by living cells, osteoinduction by growth factors, and osteoconduction by a scaffold.

Why is "It provides only a scaffold" not the answer?

A scaffold alone describes osteoconductive material such as hydroxyapatite.

Why is "It is acellular and immune-privileged" not the answer?

Autograft contains living cells, so it is not acellular.

Why is "It provides structural strength only" not the answer?

Cortical grafts provide strength, whereas cancellous graft is for biology.

What concept does this question test?

It tests Fractures: bone grafting in Orthopaedics. Its drawbacks are limited supply and donor site morbidity.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Fractures: bone grafting?

Pair each fracture with its classic complication and nerve injured. Then use the flashcards and the other Orthopaedics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.