Metabolic bone: teriparatide: practice question

A Orthopaedics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Orthopaedics · Metabolic bone: teriparatide

Sample item

Which agent used for severe osteoporosis has an anabolic action on bone when given as a daily subcutaneous injection?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Teriparatide

Teriparatide is recombinant parathyroid hormone (1-34). Intermittent exposure stimulates osteoblasts more than osteoclasts and increases bone formation, whereas continuous PTH excess causes bone loss. Treatment is limited to about 2 years, and osteosarcoma risk is a concern.

Option by option

  • A. Alendronate

    Alendronate is antiresorptive.

  • B. Teriparatide (correct)

    Correct. Intermittent PTH is anabolic.

  • C. Raloxifene

    Raloxifene is a selective oestrogen receptor modulator that is antiresorptive.

  • D. Calcitonin

    Calcitonin is a weak antiresorptive agent.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Orthopaedics questions

Questions about this Orthopaedics question

What is the answer to this Orthopaedics question?

The best answer is B, Teriparatide. Teriparatide is recombinant parathyroid hormone (1-34).

Why is "Alendronate" not the answer?

Alendronate is antiresorptive.

Why is "Raloxifene" not the answer?

Raloxifene is a selective oestrogen receptor modulator that is antiresorptive.

Why is "Calcitonin" not the answer?

Calcitonin is a weak antiresorptive agent.

What concept does this question test?

It tests Metabolic bone: teriparatide in Orthopaedics. Intermittent exposure stimulates osteoblasts more than osteoclasts and increases bone formation, whereas continuous PTH excess causes bone loss. Treatment is limited to about 2 years, and osteosarcoma risk is a concern.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Metabolic bone: teriparatide?

Pair each fracture with its classic complication and nerve injured. Then use the flashcards and the other Orthopaedics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.