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Orthopaedics · Metabolic bone: skeletal fluorosis
Sample itemAn adult from an area with high groundwater fluoride has stiffness of the spine, dense bones and ligament ossification, with genu valgum in children. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Skeletal fluorosis
Endemic skeletal fluorosis from fluoride in drinking water over 1.5 mg per litre causes osteosclerosis, calcification of ligaments and interosseous membranes, and stiffness. In children, fluorosis produces genu valgum and dental mottling. Prevention is by providing safe water.
Option by option
A. Osteomalacia
Osteomalacia produces soft bones with Looser zones.
B. Ankylosing spondylitis
Ankylosing spondylitis has sacroiliitis and is not related to water.
C. Skeletal fluorosis (correct)
Correct. Chronic fluoride excess produces dense bones and ligament calcification.
D. Osteoporosis
Osteoporosis causes bone thinning.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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