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Pediatrics · Neonatal jaundice: breast milk jaundice
Sample itemA thriving, exclusively breastfed 10-day-old term infant has a bilirubin of 12 mg/dl, normal stools and no haemolysis. What is the most likely diagnosis and best management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Breast milk jaundice; continue breastfeeding and observe
Breast milk jaundice starts after the first week, peaks at about 2 weeks and can last up to 12 weeks in a thriving baby. Feeding should continue because bilirubin is indirect and the baby is otherwise well. Biliary atresia is excluded by normal coloured stools and conjugated bilirubin.
Option by option
A. Crigler-Najjar syndrome; liver transplant
Crigler-Najjar presents with severe unconjugated jaundice in the first days.
B. Breast milk jaundice; continue breastfeeding and observe (correct)
Correct. A well baby with indirect bilirubin late in week 1 has breast milk jaundice.
C. Biliary atresia; urgent Kasai
Biliary atresia causes conjugated hyperbilirubinaemia and pale stools.
D. Haemolytic disease; exchange transfusion
Haemolytic disease presents within 24 to 48 hours.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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