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Pediatrics · Neonatology: biliary atresia
Sample itemA 5-week-old breastfed infant has persistent jaundice, pale stools and dark urine. Conjugated bilirubin is raised. What is the most appropriate surgical timing goal for the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Kasai portoenterostomy ideally before 8 weeks of age
Biliary atresia causes progressive obstruction of extrahepatic bile ducts. Outcomes of Kasai portoenterostomy are best when done before 60 days of life. Late presentation lowers the chance of clearing jaundice and many still require transplantation.
Option by option
A. No surgery needed
Untreated biliary atresia is fatal in infancy.
B. Liver transplant only as first step
Transplant is for failed Kasai or late cases.
C. Kasai portoenterostomy ideally before 8 weeks of age (correct)
Correct. Kasai is best done before 8 weeks.
D. Delay until 6 months for growth
Waiting until 6 months leads to cirrhosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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