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Pediatrics · Infections: congenital rubella
Sample itemA newborn has cataract, patent ductus arteriosus and sensorineural deafness. The mother had a rash in the first trimester. What is the most likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Congenital rubella syndrome
Congenital rubella syndrome classically has cataract, heart disease (PDA, pulmonary artery stenosis) and sensorineural deafness. Blueberry muffin rash and microcephaly can also occur. Infection in the first trimester carries the greatest risk.
Option by option
A. Congenital syphilis
Syphilis gives snuffles, rash and bone changes.
B. Congenital rubella syndrome (correct)
Correct. This triad is typical of CRS.
C. Congenital toxoplasmosis
Toxoplasmosis gives chorioretinitis and hydrocephalus.
D. Congenital CMV
CMV gives periventricular calcification and deafness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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