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Pediatrics · Infections: Kawasaki disease
Sample itemA 3-year-old has 6 days of fever, bilateral non-purulent conjunctivitis, cracked red lips, cervical lymphadenopathy and swelling of the hands. What is the treatment of choice?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. IVIG 2 g/kg with aspirin
Kawasaki disease is a medium-vessel vasculitis in which fever of 5 or more days and 4 of 5 principal features confirm the diagnosis. IVIG 2 g/kg within the first 10 days reduces coronary aneurysm risk from about 25 percent to under 5 percent. Aspirin is given for its anti-inflammatory and later antiplatelet effect.
Option by option
A. Oral steroids alone
Steroids alone are not standard first-line.
B. Observation
Untreated disease leads to coronary aneurysms.
C. IVIG 2 g/kg with aspirin (correct)
Correct. IVIG with aspirin is standard.
D. Penicillin
Penicillin treats streptococcal infection and does not apply here.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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