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Pediatrics · Infections: congenital toxoplasmosis
Sample itemA newborn has hydrocephalus, chorioretinitis and diffuse intracranial calcifications. The mother had contact with cats. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Congenital toxoplasmosis
The classic triad of toxoplasmosis is hydrocephalus, chorioretinitis and intracranial calcifications. Maternal infection is acquired from cat faeces or undercooked meat. Treatment is pyrimethamine, sulfadiazine and folinic acid.
Option by option
A. Neonatal herpes
Neonatal herpes causes skin and CNS disease.
B. Congenital CMV
CMV calcifications are periventricular.
C. Congenital rubella
Rubella gives cataract and heart disease.
D. Congenital toxoplasmosis (correct)
Correct. This triad indicates toxoplasmosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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