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Pediatrics · Cardiology: infective endocarditis
Sample itemA child with a VSD has fever for 2 weeks, new murmur, splinter haemorrhages and Roth spots. What is the most common causative organism in this setting?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Viridans streptococci
Subacute bacterial endocarditis on congenitally abnormal valves or defects is most commonly caused by viridans streptococci. Diagnosis uses modified Duke criteria, with at least 2 or 3 blood cultures before antibiotics. Staphylococcus aureus is the leading cause in acute disease.
Option by option
A. Viridans streptococci (correct)
Correct. Viridans streptococci are the commonest.
B. Staphylococcus epidermidis
Coagulase-negative staphylococci typically infect prosthetic material.
C. Candida albicans
Candida occurs in immunocompromised patients and in IV drug use.
D. Escherichia coli
E. coli is rare in endocarditis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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