Haematology: haemophilia A: practice question

A Pediatrics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pediatrics · Haematology: haemophilia A

Sample item

A 2-year-old boy has haemarthrosis of the knee after minor trauma. aPTT is prolonged with normal PT and platelet count, and factor VIII is low. What is the treatment during a bleed?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Factor VIII concentrate

Haemophilia A is X-linked recessive factor VIII deficiency, and bleeds are treated by factor VIII replacement with the dose calculated by target level. Emicizumab is used for prophylaxis. Desmopressin may help in mild disease, and IM injections are avoided.

Option by option

  • A. Factor VIII concentrate (correct)

    Correct. Replace factor VIII.

  • B. Vitamin K

    Vitamin K deficiency is not the problem.

  • C. Fresh frozen plasma as first choice

    FFP is used only when concentrates are unavailable.

  • D. Platelet transfusion

    Platelet counts are normal.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pediatrics question

What is the answer to this Pediatrics question?

The best answer is A, Factor VIII concentrate. Haemophilia A is X-linked recessive factor VIII deficiency, and bleeds are treated by factor VIII replacement with the dose calculated by target level.

Why is "Vitamin K" not the answer?

Vitamin K deficiency is not the problem.

Why is "Fresh frozen plasma as first choice" not the answer?

FFP is used only when concentrates are unavailable.

Why is "Platelet transfusion" not the answer?

Platelet counts are normal.

What concept does this question test?

It tests Haematology: haemophilia A in Pediatrics. Emicizumab is used for prophylaxis. Desmopressin may help in mild disease, and IM injections are avoided.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Haematology: haemophilia A?

Memorise milestones and the vaccine schedule as tables and revise them often. Then use the flashcards and the other Pediatrics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.