Oncology: osteosarcoma: practice question

A Pediatrics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pediatrics · Oncology: osteosarcoma

Sample item

A 14-year-old has pain around the knee and an X-ray showing a metaphyseal lesion with sunburst periosteal reaction and Codman triangle. What is the commonest site of metastasis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Lung

Osteosarcoma is the commonest primary malignant bone tumour in adolescents and typically arises at the distal femur and proximal tibia. Lung is the major site of metastasis. Treatment is neoadjuvant chemotherapy, limb salvage surgery and adjuvant chemotherapy.

Option by option

  • A. Lung (correct)

    Correct. Lung is the most frequent site.

  • B. Spleen

    Spleen metastasis is rare.

  • C. Brain

    Brain metastasis is rare.

  • D. Liver

    Liver metastasis is uncommon.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pediatrics questions

Questions about this Pediatrics question

What is the answer to this Pediatrics question?

The best answer is A, Lung. Osteosarcoma is the commonest primary malignant bone tumour in adolescents and typically arises at the distal femur and proximal tibia.

Why is "Spleen" not the answer?

Spleen metastasis is rare.

Why is "Brain" not the answer?

Brain metastasis is rare.

Why is "Liver" not the answer?

Liver metastasis is uncommon.

What concept does this question test?

It tests Oncology: osteosarcoma in Pediatrics. Lung is the major site of metastasis. Treatment is neoadjuvant chemotherapy, limb salvage surgery and adjuvant chemotherapy.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Oncology: osteosarcoma?

Memorise milestones and the vaccine schedule as tables and revise them often. Then use the flashcards and the other Pediatrics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.