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Pediatrics · Neurology: status epilepticus
Sample itemA 4-year-old has a generalised seizure continuing for 10 minutes. IV access is not yet available. Which is the best first-line drug?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intranasal or buccal midazolam or rectal diazepam
Benzodiazepines are first line, via the intranasal, buccal or rectal route when there is no IV access, or IV lorazepam or diazepam if available. If seizures persist, a second-line drug such as IV phenytoin, levetiracetam or valproate is given. Blood glucose is checked.
Option by option
A. Intramuscular phenytoin
IM phenytoin is erratically absorbed and is not used.
B. Oral phenobarbitone
Oral drugs are unsafe in an actively seizing child.
C. Intranasal or buccal midazolam or rectal diazepam (correct)
Correct. A benzodiazepine by an accessible route.
D. Oral carbamazepine
Carbamazepine has no parenteral form for emergency use.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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