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Pediatrics · Neurology: Lennox-Gastaut syndrome
Sample itemA 4-year-old has multiple seizure types including tonic and atonic drops, intellectual disability and EEG showing slow spike-and-wave of 1.5 to 2.5 Hz. Which is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Lennox-Gastaut syndrome
Lennox-Gastaut syndrome is a severe epileptic encephalopathy with multiple seizure types, cognitive impairment and slow spike-and-wave on EEG, which is often a progression from infantile spasms. It is difficult to control. Valproate, lamotrigine, clobazam and rufinamide are used.
Option by option
A. Juvenile myoclonic epilepsy
Juvenile myoclonic epilepsy begins in adolescence with morning jerks.
B. Lennox-Gastaut syndrome (correct)
Correct. This triad is Lennox-Gastaut.
C. Benign rolandic epilepsy
Rolandic epilepsy is benign.
D. Childhood absence epilepsy
Absence epilepsy has 3 Hz spike-and-wave and normal intellect.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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