Antidepressants: bupropion: practice question

A Psychiatry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

Try it

Psychiatry · Antidepressants: bupropion

Sample item

Which statement about bupropion is correct?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. It lowers the seizure threshold and is contraindicated in bulimia nervosa

Bupropion is a norepinephrine-dopamine reuptake inhibitor that is also used for smoking cessation. It has little sexual dysfunction or weight gain, but causes seizures at high doses, especially in bulimia and eating disorders.

Option by option

  • A. It causes marked weight gain

    It is weight-neutral or causes weight loss.

  • B. It is a pure serotonin reuptake inhibitor

    It acts on noradrenaline and dopamine reuptake.

  • C. It lowers the seizure threshold and is contraindicated in bulimia nervosa (correct)

    Correct. Seizure risk makes it unsuitable in bulimia.

  • D. It commonly causes sexual dysfunction

    Sexual dysfunction is uncommon and it is used to treat SSRI-induced dysfunction.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Psychiatry questions

Questions about this Psychiatry question

What is the answer to this Psychiatry question?

The best answer is C, It lowers the seizure threshold and is contraindicated in bulimia nervosa. Bupropion is a norepinephrine-dopamine reuptake inhibitor that is also used for smoking cessation.

Why is "It causes marked weight gain" not the answer?

It is weight-neutral or causes weight loss.

Why is "It is a pure serotonin reuptake inhibitor" not the answer?

It acts on noradrenaline and dopamine reuptake.

Why is "It commonly causes sexual dysfunction" not the answer?

Sexual dysfunction is uncommon and it is used to treat SSRI-induced dysfunction.

What concept does this question test?

It tests Antidepressants: bupropion in Psychiatry. It has little sexual dysfunction or weight gain, but causes seizures at high doses, especially in bulimia and eating disorders.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antidepressants: bupropion?

Learn each diagnosis by its core features and its first-line treatment. Then use the flashcards and the other Psychiatry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.