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Psychiatry · Psychopharmacology: rapid tranquilisation
Sample itemA violent, agitated patient in the emergency department requires rapid tranquilisation. Which combination is commonly recommended?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intramuscular haloperidol with promethazine, or lorazepam
Haloperidol with an anticholinergic antihistamine such as promethazine (which reduces dystonia and adds sedation) or a benzodiazepine like lorazepam is used. The patient's airway, respiratory rate and vital signs must be monitored afterwards.
Option by option
A. Intravenous potassium
Potassium has no role.
B. Oral disulfiram
Disulfiram is used for alcohol relapse prevention.
C. Intramuscular haloperidol with promethazine, or lorazepam (correct)
Correct. IM haloperidol plus promethazine, or lorazepam, is standard.
D. Oral lithium
Lithium has a slow onset and is unsuitable.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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