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Psychiatry · Substance use: delirium tremens
Sample itemOn day 3 after admission for a femur fracture, a chronic drinker is disorientated, sees insects crawling on the wall, and has tachycardia, fever and coarse tremor. The best initial drug treatment is:
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Benzodiazepines such as lorazepam or diazepam with thiamine
Delirium tremens is a medical emergency with a mortality that is significant if untreated. Benzodiazepines are first-line, thiamine is given to prevent Wernicke encephalopathy, and antipsychotics alone lower the seizure threshold.
Option by option
A. Disulfiram
Disulfiram given during withdrawal could cause a toxic reaction and has no role.
B. Benzodiazepines such as lorazepam or diazepam with thiamine (correct)
Correct. Benzodiazepines plus thiamine are the cornerstone.
C. Naltrexone
Naltrexone is for relapse prevention.
D. Haloperidol alone
Haloperidol alone lowers seizure threshold and does not prevent progression.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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