Endocrine: MEN 2B: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Surgery · Endocrine: MEN 2B

Sample item

A young man has marfanoid habitus, mucosal neuromas of the lips and tongue, and medullary thyroid carcinoma. Which syndrome is this?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. MEN 2B

MEN 2B comprises medullary thyroid carcinoma, phaeochromocytoma, mucosal neuromas and marfanoid habitus due to a RET mutation, and hyperparathyroidism is typically absent. MEN 2A includes medullary carcinoma, phaeochromocytoma and parathyroid hyperplasia. MEN 1 involves parathyroid, pituitary and pancreatic tumours.

Option by option

  • A. MEN 2A

    MEN 2A lacks mucosal neuromas and marfanoid habitus.

  • B. MEN 1

    MEN 1 does not involve medullary thyroid cancer.

  • C. MEN 2B (correct)

    Correct. Neuromas with marfanoid habitus define MEN 2B.

  • D. Von Hippel-Lindau disease

    VHL involves haemangioblastoma and renal carcinoma.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Surgery questions

Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is C, MEN 2B. MEN 2B comprises medullary thyroid carcinoma, phaeochromocytoma, mucosal neuromas and marfanoid habitus due to a RET mutation, and hyperparathyroidism is typically absent.

Why is "MEN 2A" not the answer?

MEN 2A lacks mucosal neuromas and marfanoid habitus.

Why is "MEN 1" not the answer?

MEN 1 does not involve medullary thyroid cancer.

Why is "Von Hippel-Lindau disease" not the answer?

VHL involves haemangioblastoma and renal carcinoma.

What concept does this question test?

It tests Endocrine: MEN 2B in General Surgery. MEN 2A includes medullary carcinoma, phaeochromocytoma and parathyroid hyperplasia. MEN 1 involves parathyroid, pituitary and pancreatic tumours.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Endocrine: MEN 2B?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.