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General Surgery · Head and neck: oral premalignant lesions
Sample itemAmong oral premalignant lesions, which has the highest rate of malignant transformation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Erythroplakia
Erythroplakia, a red velvety patch, shows dysplasia or carcinoma in situ in most biopsies and has the highest risk of malignancy. Non-homogeneous leukoplakia is the next riskiest. Biopsy of any persistent lesion is advised, along with cessation of tobacco and areca nut.
Option by option
A. Erythroplakia (correct)
Correct. Erythroplakia is the highest-risk lesion.
B. Homogeneous leukoplakia
Homogeneous leukoplakia has a lower risk.
C. Lichen planus
Lichen planus carries a small risk.
D. Aphthous ulcer
Aphthous ulcers are benign.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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