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General Medicine · Infectious disease
Sample itemWhat is the drug of choice for Pneumocystis jirovecii pneumonia in a patient with advanced HIV?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Trimethoprim–sulfamethoxazole
Cotrimoxazole is the first-line drug for treatment and prophylaxis. Steroids are added in moderate to severe disease with hypoxia.
Option by option
A. Fluconazole
Fluconazole is for candidiasis and cryptococcosis.
B. Trimethoprim–sulfamethoxazole (correct)
Correct.
C. Amphotericin B
Amphotericin B is for invasive fungal infections such as cryptococcal meningitis.
D. Ganciclovir
Ganciclovir treats CMV.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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