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Dentistry · Oral medicine and oral cancer: HPV-related lesions
Sample itemAn 8-year-old from a rural community has multiple soft, pale, flat-topped papules on the lower lip and buccal mucosa, which regress after months. Which virus is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. HPV types 13 and 32
Focal epithelial hyperplasia (Heck disease) is caused by HPV 13 and 32 and often affects children in families or communities. It is benign and may regress.
Option by option
A. Coxsackie A16
Coxsackie A16 causes hand, foot and mouth disease with vesicles.
B. HPV types 13 and 32 (correct)
Correct. HPV 13 and 32 cause Heck disease.
C. HPV types 16 and 18
HPV 16 and 18 are high-risk oncogenic types linked to carcinoma.
D. Herpes simplex virus 2
HSV-2 causes genital herpes and occasional oral vesicles, not papules.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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